Tired of hiding her true identity when dating normal guys, Sabrina agrees to be fixed up by Zelda with a handsome and charming witch named Derek, but the budding romance is threatened when she realizes his family harbors anti-mortal sentiments.
Derek is the third witch boy that Sabrina dates, following Dante and Dashiell.
Bryan Kirkwood, who plays Derek in this episode, was dating Melissa Joan Hart at the time this episode was made.
Dr. Axelrod mentions that Derek attends Boston College and is on the hockey team. Harvey is also apart of the Boston College Hockey Team, so it is possible that the two knew each other.
Sabrina mentions an unseen time when Harvey accidentally tasted a potion that her aunts were making that caused his tongue to grow fur.
Sabrina says that she has vacationed on Jupiter three summers in a row.
Salem bleaches his teeth bright white, in this episode.
The title of this episode comes from the line "Some of my best friends are..." A line used when someone is attempting to justify their prejudices. An example comes straight from this episode when it is said, "Some of my best friends are half-mortals, I just don't want them living in my neighborhood." Obviously, alluding to the issue of racism/prejudice in society.
Anti-mortal thinking has been seen previously from Maw-Maw in Witch Trash.
Sabrina magically gags Salem with gaffa-tape at one point in this episode. Zelda uses the exact same spell on Salem in Season Six's A Birthday Witch.
Upon seeing Derek for the first time in the coffeehouse, Hilda remarks to Josh, "Does he have an older brother, or a twin?" Bryan Kirkwood does have a twin brother, also an actor, but Bryan is older by six minutes.
During Dinner at the Axelrods', Dr. Axelrod tells Sabrina that she has a perfect bite, but In the episode, Sabrina's Real World, Sabrina, when confronted with her sleep drool, admits that she has an overbite, and not a perfect bite.